Tarlov Cyst Research Library

Curated evidence archive

The Tarlov Cyst Research Library

A collection of Tarlov Cyst research papers from around the world. Searchable by title, keyword, publication year, and country of origin.

155
Papers indexed
35
Countries
20
Must reads

Research Papers (155)

Navigating Surgical Strategies for Symptomatic Tarlov Cysts: A Case Report of Successful Microsurgical Excision and Imbrication

2025 · Indonesia

Tarlov CystMicrosurgical ExcisionImbricationNerve Root Decompression

This case report details the successful treatment of a symptomatic sacral Tarlov cyst causing severe pain. Surgeons performed microsurgical partial excision and wall imbrication to decompress the nerve root and prevent CSF leakage. The patient experienced total pain relief and complete functional recovery over a one-year follow-up.

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Surgical Intervention is Associated with Improvement in Health-Related Quality of Life Outcomes in Patients with Symptomatic Sacral Tarlov Cysts: Results from a Prospective Longitudinal Cohort Study

2024 · USA

FeigenbaumSurgeryPositive Outcome

In a study of 144 Tarlov cyst patients, over 80% reported significant improvement in quality of life one year after surgery, regardless of age or how long they had symptoms. Patients were considered to have a large cyst at the 1.5cm threshold.

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Symptomatic lumbar Tarlov cyst resolution after computed tomography-guided percutaneous trans-sacral fibrin glue intracystic injection: A case report and literature review

2024 · Italy/Switzerland

AFGIAspirationInjectionFoot Drop

40-year-old female presented with the 2-year onset of a partial left foot drop attributed to an L5 Tarlov cyst. Following a CT-guided percutaneous trans-sacral fibrin glue intracystic injection, the cyst largely resolved, and the patient became asymptomatic.

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Uncommon cause of radiculopathy: A case of symptomatic Tarlov cyst in an elderly female and literature review

2024 · Nepal/India

20%Conservative Treatment

63 year old with 1.2 cm Tarlov Cyst causing worsening lower back and left buttock pain radiating down her left leg, along with sharp shooting discomfort, toe numbness and tingling, and a slightly reduced left ankle jerk reflex, all of which were exacerbated by walking, standing, coughing, or climbing stairs. Tarlov cysts are uncommon and underdiagnosed, with notable complexities in diagnosis and management.

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Accurate diagnosis and treatment of sacral meningeal cysts without spinal nerve root fibres: Identifying leakage orificium using high-resolution spherical arbitrary-dimensional reconstructing magnetic resonance imaging

2024 · China

Meningeal DiverticulaMD CystDr.SunExtradural

This study discusses an MRI technique (arbitrary-dimensional nerve root reconstruction magnetic resonance imaging) to identify the ostium where cerebral spinal fluid is leaking into Meningeal Diverticulum cysts (without nerve roots inside)

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Successful Conservative Management of a Patient With Symptomatic Cervical Perineural Cysts: A Case Report

2024 · Greece

SteroidsShort-term follow upCase Study

56-year-old female patient with symptomatic Cervical Tarlov cysts C6–C7 & C7-T1 treated conservatively with a 14-day tapering course of oral corticosteroids. EMG showed reduced recruitment of the triceps and extensor digitorum communis with no automatic activity, indicating possible acute C7 nerve root damage. Symptomatic cervical perineural cysts are exceedingly rare.

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A bibliometric and visualization study of global research trends in sacral Tarlov cyst from 2000 to 2022

2024 · China

Despite sacral Tarlov cysts severely impacting patient quality of life, comprehensive quantitative analyses mapping the evolution and current direction of global research on this neurological condition have historically been lacking. Researchers analyzed 930 studies published between 2000 and 2022 to map global research trends, major contributors, and emerging clinical focuses in sacral Tarlov cyst research.

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Thecaloscopy Reduces the Risk of Recurrent Perineural (Tarlov) Cysts after Microsurgical Resection

2024 · Germany

Retrospective study evaluated whether combining thecaloscopy (endoscopic arachnoid sheath fenestration) with traditional microsurgical resection reduces the recurrence of symptomatic sacral Tarlov cysts in 78 patients. The authors found that adding thecaloscopy significantly lowered cyst recurrence to 10.4% compared to 30% for those receiving microsurgical resection alone, while maintaining a low complication rate.

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Editorial: Microsurgical treatment of sacral Tarlov cysts

2022 · USA

Editorial commentators Porche and Hoh raise concerns regarding strictness of surgical selection criteria, missing diagnostic predictors, potential cohort biases, and a lack of standardized outcome measures in the original study by Chu et al. In response, Chu et al. defend their clinical approach, detail their rigorous screening process to rule out alternative pathologies, and acknowledge the necessity for prospective, multicenter trials to establish standardized treatment protocols.

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High Prevalence of Small-Fiber Neuropathy in Patients with Tarlov Cysts: Toward a More Comprehensive Clinical Understanding

2025 · Belgium

PGADNeuropathic PainhEDSCerebrospinal fluid pressurePersistent Genital Arousal Disorder

Tarlov Cysts can be associated with elevated spinal fluid pressure within the nerve root sheath. Elevated pulsatile CSF underlies the formation of TCs at the dorsal root ganglion and may gradually contribute to small-fiber dysfunction by irritating, compressing and damaging small nerve fibers within the dorsal root ganglion.

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